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Mitochondria from both hemispheres of male rat brain had more impairment of state 3 (Complex I dependent, ADP stimulated) respiration compared to mitochondria from female brain after HI, and the respiration was 30% lower in mitochondria from male brain after HI, than in sham rat pups [38]

If left untreated, it can cause unconsciousness (coma) and sometimes even death., and to the build up of harmful substances in the blood

Multiple studies have proved that for TMAO to induce inflammatory gene expression in leukocytes and both cell types, nuclear factor kappa B signaling has to be activated [69]

9 While the complement system helps eliminate pathogens, chronic activation leads to immune system imbalances

The body tissue distribution studies show a very high concentration of LC in mature spermatozoa and luminal fluid of cauda epididymis [26]

NF-B: nuclear factor B