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Impact of FAK expression on the cytotoxic effects of CIK therapy in triple-negative breast cancer

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[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Nauman G., Gray J.C., Parkinson R., Levine M., Paller C.J

4.2 Targeting Gln metabolism to inhibit tumor proliferation 4.2.1 Inhibition of Gln uptake Tumor survival and proliferation are heavily dependent on Gln, a hydrophilic amino acid that must be transported into tumor cells by transmembrane proteins, such as SLC1A5, SLC6A14, and SLC38A1/2

In addition to contributing to the development of fatty liver, the increases in NADH levels resulting from the ADH-mediated breakdown of alcohol also may play a role in the formation of scar tissue that characterizes fibrosis, a more severe stage of liver disease