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Studies have shown [6] that SIRT4 can inhibit fatty acid oxidation in hepatocytes and muscle cells, therefore, GDH may be involved in lipid metabolism through SIRT4

coli BL21(DE3) using 0.5 mM IPTG induction at 37C for 6 h and purified initially using Ni 2+ -affinity chromatography (HiTrap IMAC FF, Cytiva)

Furthermore, elevated levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NOS, further complicate this scenario by reducing NO bioavailability (Raghavan and Dikshit, 2004

Clathrin adaptor GGA1 modulates myogenesis of C2C12 myoblasts

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