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(2000) demonstrated that the GHK-Cu complex directly stimulated MMP-2 expression (gelatinase A) in fibroblast cultures, while other research documented differential effects on collagenolytic activity

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Gene expression studies show GHK-Cu modulates 4,000+ human genes, resetting expression patterns toward a healthier, more youthful state

doi: 10.1186/s12879-018-2991-2

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Cutting edge: Distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory cd4+ T cell subsets