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Mercer LK, Askling J, Raaschou P et al (2017) Risk of invasive melanoma in patients with rheumatoid arthritis treated with biologics: results from a collaborative project of 11 European biologic registers

They may also cause lower sperm counts
It's doubly important for vitamin B12 deficiency to be diagnosed and treated as soon as possible

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doi:10.1186/s12970-017-0176-9 Lewis EJH, Perkins BA, Lovblom LE, Bazinet RP, Wolever TMS, Bril V