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Dadurch kann die Bindung zwischen dem Kupferion und dem Peptid unterbrochen werden, wodurch das Produkt unbrauchbar wird oder mglicherweise schwere Hautreizungen verursacht

Translational percentages (concordance rates) of results exhibit a wide range from 0100% with no predictable factors for translational success or failure in humans (309), and even multiple experiments fail to significantly contribute to improving the reproducibility of animal testing, accounting for 41%72% of the observed total variance (310, 311)

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Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies