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An open label, phase I trial showed safety and tolerability of unilateral, subthalamic AAV-GAD injection, as well as significant improvements in the UPDRS motor score, predominantly on the side of the body that was contralateral to surgery up to 12 months after treatment (Kaplitt et al

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238 In focal brain infection, brain abscesses instigate classical inflammatory responses, with reactive astrogliosis, infiltration of macrophages and stromal cells, formation of fibrotic scar and erection of glial perilesional barrier

Morphologically, ferroptotis-experiencing cells, including HK-2, MC3T3, and hFOB 1.19 cells, exhibited reduced mitochondrial volume and cristae, and increased mitochondrial membrane density in diabetes ( Table 1 )

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