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Of note, the intracellular glutamine but not glutamate was significantly increased 3 h after the glutamate and NH 4 Cl co-treatment, suggesting that astrocytes elevated the expression of GS to accelerate the production of glutamine via condensation of ammonia with glutamate (Supplementary Fig

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Phytochelatin synthase is regulated by protein phosphorylation at a threonine residue near its catalytic site

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