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Of the 28 869 genes represented on the GeneChip Human Gene 1.0 ST array, 439 genes were identified to be differentially expressed, with a significance P 1.5 (Supplementary Table S2)

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In a transgenic mouse model exhibiting age-associated tau pathology, melatonin treatment efficiently decreased the hyperphosphorylation of tau [115]

10.1007/BF02536408

doi: 10.1128/JVI.02550-07

Similarly, patients with pituitary gland removal or those unresponsive to minoxidil or finasteride may benefit from IGF-1-based therapies as a supplementary or alternative approach [61]