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We also summarize newly proposed mechanisms associated with hepatoprotection and tumor suppression, such as attenuation of hepatocellular stress through inhibition of the NEDD9/FAK/AKT cascade and a potential role in cell-cycle regulation via the HDAC/p21 axisalthough the latter remains to be validated in MASLD-specific models

doi: 10.1111/an-dr.12191

Cereal foods are the major source of betaine in the Western dietanalysis of betaine and free choline in cereal foods and updated assessments of betaine intake

Acetyl-L-carnitine, for instance, crosses the blood-brain barrier more readily and has been studied for neurological applications

The muscular structure of modern-day bison is thought to be very close to their original and natural form

McLaughlin, M.D., Phoebe H