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Reference sources: Sigma-Aldrich 5-Amino-1MQ (SML2832) | NIH PMC NNMT Inhibitor Research Regulatory Notice 5-Amino-1MQ is an unapproved new drug compound

Reconstitution technique also plays a role

Trace impurities generated during synthesis and storage can be simultaneously separated and detected, ensuring the preparation purity is 98%

Clinical studies have shown results can last for one year or more

Methylcobalamin is an active form of vitamin B12 that helps in synthesis of methionine and S-adenosylmethionine

All patients signed an informed consent form and consented to the disclosure of imaging data