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Further analysis suggested that the expression of TGFBI to correlate positively with the expression of identified and validated proteins such as GFPT2, FLNA, G6PD, ITGAV, ITGA1 and ITGA2

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These findings suggest that alterations in the excitatory neurotransmission regulation, presumably increased cycling of the Gln-Glu circuit, may underlie the pathophysiology of ASD.

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