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Red flags that need care Seek urgent medical help if sleep problems come with chest pain, trouble breathing, fainting, confusion, hallucinations, seizure, severe agitation, suicidal thoughts, or a serious allergic reaction

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Some studies (3234) have shown that HIF-1 gene expression is enhanced in neonatal rats after the onset of hypoxic-ischemic encephalopathy, mainly manifesting as enhanced HIF-1 expression at both the mRNA and protein levels in brain tissue

Kanaide M, Uezono Y, Matsumoto M, Hojo M, Ando Y, Sudo Y, Sumikawa K, Taniyama K (2007) Desensitization of GABAB receptor signaling by formation of protein complexes of GABAB2 SUBUNIT WITH GRK4 Or GRK5

HAP1 also colocalizes and interacts with kinesin light chain [71]
