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Prior to oxidation, PUFAs must undergo enzymatic activation and incorporation into membrane phospholipids

Rodent studies have used approximately 1 to 10 micrograms per kilogram of body weight, often administered subcutaneously or intraperitoneally

Introduction Migraine, a disorder influenced by genetics and characterized by multiple factors involving neurological, glial, and vascular systems, ranks as the second most debilitating condition worldwide, impacting the health of over one billion individuals globally (1)

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Li, Z.-D

Cell viability Cells were grown until approximately 80% confluency and then harvested by trypsinization and seeded onto 96 well tissue culture plates at a density of 10,000 cells per well and allowed to adhere for at least 6 hours prior to treatment