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We found spatial and reversal learning deficits, as well as large-scale mPFC transcriptional changes in pathways associated with glutamate and GABA signaling, in stress-exposed C-Glud1+/ mice, but not in their stress-nave or C-Glud1+/+ littermates

Although differences were found between administration routes at week 52, the probability that the differences were below the non-inferiority threshold was very low