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[36] The hydrolysis of phospholipids in the membrane can lead to hemolysis and necrosis of muscle cells

Ackerman AB, MaganaGarcia M

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3.1.5 Ritlecitinib (PF-06651600) and Brepocitinib (PF-06700841) Ritlecitinib, an irreversible inhibitor of JAK3 and tyrosine kinase applicable to the treatment of moderate-to-severe RA (40) and Brepocitinib, a TYK2/JAK1 inhibitor, are currently undergoing evaluation of their efficacy and safety profile in active NSV in combination with phototherapy (NCT03715829) (41)