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DSIP, or delta sleep-inducing peptide, is a nine-amino-acid neuropeptide first isolated in 1974 from the cerebral venous blood of sleeping rabbits

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10.1083/jcb.200712039 373 Van LangenhoveT.Van Der ZeeJ.Van BroeckhovenC

Terkeltaub R, Banka CL, Solan J, Santoro D, Brand K, Curtiss LK

The course of peptide administration was continued for seven days

(2020) Ergothioneine, a metabolite of the gut bacterium Lactobacillus reuteri, protects against stress-induced sleep disturbances