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It has been studied extensively in colitis models, where it reduces intestinal inflammation through the same NF-kB suppression mechanism that benefits skin inflammation

Neutrophil activation and adhesion to endothelial cells amplify the inflammatory response, resulting in endothelial dysfunction and exacerbating tissue injury [8]

Han Z, Sergeeva O, Roelle S, Cheng H, Gao S, Li Y, et al
The wide range of variations was attributed to the altered body metabolism of diabetic patients

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J Vet Pharmacol Ther
