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Description
Oxidative stress mediates end-organ damage in a novel model of acetaminophen-toxicity in Drosophila

These results directly confirm that excessive NNMT activation suppresses NAD+ synthesis and impairs energy metabolism, while NNMT inhibition effectively reverses this process, establishing NNMT as a negative regulator of energy metabolism

2020;3:e204693e204693
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At their core, peptides are small chains of amino acids that act like signaling molecules in the body

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Hohberger, B
