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References 1.Toussaint K, Yang XC, Zielinski MA, Reigle KL, Sacavage SD, et al

Aqueous solubility facilitates transport within the blood and excretion via the kidney, while a lipophilic chelator may exhibit greater penetration of cellular membranes (including those within the central nervous system) to chelate intracellular elements

doi: 10.1023/a:1006169717355

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