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10.1074/jbc.M115.659680 [DOI] [PMC free article] [PubMed] [Google Scholar] Toyokuni S., Okamoto K., Yodoi J., and Hiai H

We highlight critical gaps in current nanomedicine research, including biocompatibility and toxicity concerns, scalability and cost-effectiveness of production, and the need for personalized medicine and patient-specific nanotherapies

Choi, Emerging signals modulating potential of ginseng and its active compounds focusing on neurodegenerative diseases, Journal of Ginseng Research 43(2) (2019) 163-171

Specifically, patients who have signs indicative of WE should be treated empirically with a minimum of 500mg thiamine hydrochloride per 100mL of normal saline, given by infusion over a period of 30 minutes, three times per day for 2 to 3 days

doi: 10.3389/fmicb.2019.01586 340 AlvesMJFerreiraICFroufeHJAbreuRMMartinsAPintadoM

Clear explanation of risks : Any doctor proposing an off-label procedure has an ethical obligation to discuss all known risks, including those described in the section above