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Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, et al
J Biol Chem 275:2508225088 Du J, Feng L, Zaitsev E, Je HS, Liu XW, Lu B (2003) Regulation of TrkB receptor tyrosine kinase and its internalization by neuronal activity and Ca 2+ influx

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Deficiencies are linked to Alzheimer's/Dementia, Parkinson's, Cancers, Auto-Immune, Cardiovascular Disease, Diabetes, Mast Cell Activation Syndrome, and so much more

S2J+K) and FOXO4 knockout mice do not show a striking phenotype (Hosaka et al., 2004
