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By blocking the channels, cisplatin interferes with potassium ion flow, which disrupts normal neuronal signaling

(Berlin: Springer) 215233

reported 67 human cases of H5N1, of which 40 were linked to exposure to diseased cattle (PAHO/WHO, 2025)

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As a polyphenol, fisetin can counteract oxidative stress and mediate immune response via AMPK/SIRT1 and Nfr2 pathways (see Figure 1 )
In summary, the highly interconnected nature of redox homeostasis and glycolysis in cancer cells provides an opportunity for synthetic lethal drug combinations targeting GSH synthesis and glucose metabolism
