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Shaking creates foam, denatures protein at the air-liquid interface, and reduces potency

Zhao ZY, Liang L, Fan X, et al

2018 Sep 18;10(9):1321

[DOI] [PubMed] [Google Scholar] 9.Gibson WT, Farooqi IS, Moreau M, DePaoli AM, Lawrence E, O'Rahilly S, Trussell RA

Pain modulation and interaction with endogenous opioid systems represent another productive area of DSIP investigation

The increased ROS generation and mitochondrial activity are the results of the high metabolic needs of the cochlea, particularly in the sensory hair cells and stria vascularis [23]
