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SLC7A7 is a cationic amino acid transporter which is abnormally upregulated in the kidney tissue of DKD and shows a positive correlation with the ferroptosis driver ACSL4 and fibrosis markers, including -smooth muscle actin (-SMA) and collagen type Ia 1 ( Col1a1 ) (Zhao et al., 2025a)
Surprisingly, some may initially experience a worsening of their condition
10.1097/GME.0000000000001319 33
QinYShiWZhuangJLiuYTangLBuJet al
These are individual issues in clinical practice, but they should not be ignored (we should never rely on standardized tables)
