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By stimulating the pituitary gland, MK-677 increases circulating levels of growth hormone and IGF-1

doi: 10.1053/J.GASTRO.2015.02.006 181 KanagarathamCel AnsariYSLewisOLOettgenHC

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It was demonstrated that DUX4 expression supports accumulation of HA in DUX4 -expressing cells and that multiple DUX4 -induced molecular pathologies are mediated by HA which accumulates following DUX4 induction