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S.TsaiS

Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate -lyase/glutamine transaminase K

doi: 10.1016/j.cell.2011.11.016 81 ThieryJP

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More specifically, GPX4 inhibits ferroptosis by reducing each PUFA-OOH to the corresponding PUFA-OH and oxidizing GSH (a reductive cofactor of GPX4) to GSSG (oxidized GSH) (Figure 1B) (Ma et al., 2022a)
Seminars in oncology
