glutathione reaction hepatic gsh to gssg. Chemical structure of two isoforms of (GSH and GSSG) Frontiers | Glutathione: Pharmacological aspects

E., Gottlieb, R

Increased ROS production and/or reduced antioxidant defenses lead to the accumulation of dysfunctional proteins, lipids and nucleic acids (including mtDNA) and impaired mitophagy

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Though LA has long been touted as an antioxidant, it has also been shown to improve glucose and ascorbate handling, increase eNOS activity, activate Phase II detoxification via the transcription factor Nrf2, and lower expression of MMP-9 and VCAM-1 through repression of NF-kappa-B

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It also soothes redness, inflammation, and discomfort of the skin