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3 It has been estimated that glaucoma is the second cause of blindness in humans and that 68 million patients suffer from this pathology, about seven million individuals having bilateral blindness

doi: 10.1016/j.bbamcr.2016.01.023 12 PlacidiMEmidioGDVirmaniAD'AlfonsoAArtinPGD'AlessandroAMet al

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Second, non-specific permeability to any small molecules provided by the opening of the mPTP triggers mitochondrial swelling [189]
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