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In the UK, adults aged 15 and over require 1.5 micrograms (mcg) per day, according to the Department of Health's Reference Nutrient Intake

Medications Sometimes certain medications can also contribute to vitamin B12 deficiency

In CLL, leukemia progression consists of recirculation of cancer cells from the blood to the lymphoid organs, and this process is coordinated by the chemokine CXCL12 and its receptor CXCR4 [31]

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