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These disorders include DD [135,136,137,138,139,140], ALS [141], AD [142,143,144], HE [145,146], etc
In a murine model of pulmonary granulomatous inflammation, PPAR expression and activity in alveolar macrophage were significantly reduced 60 days after multi-walled carbon nanotube (MWCNT) exposure
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injection 20 minutes prior to injection of labeled glucose led to a reduction in the oxidation of [U- 14 C]glucose for energy and in the incorporation of 13 C into amino acids and tricarboxylic acid cycle intermediates, consistent with sparing of glucose by use of the acetyl CoA from ALCAR for energy in brain

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