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Intersection analysis of the NP targets and SCA3-related genes revealed 33 potential therapeutic targets within the MAPK signaling pathway, including CACNA1B, TNF, CACNA1H, RELA, EGFR, IKBKB, RPS6KA3, IRAK1, ERBB2, RPS6KA1, AKT1, MAPK1, IKBKG, PRKACA, MAP4K4, PRKCG, MAP4K2, HSPA8, JUN, MAP2K2, DUSP3, CHUK, PRKCA, MAPK14, VEGFA, PPM1A, TAOK1, IL1B, MAPKAPK2, MAPT, TP53, MAP3K14, and HSPA1A (Table S12)

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The neurotropic vitamins B1, B6 and B12 are the unsung heroes of nerve health

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