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Iron overload, oxidative stress and vascular dysfunction: Evidences from clinical studies and animal models
This process is often accompanied by up-regulation of intracellular labile iron, transferrin and malondialdehyde (MDA), and down-regulation of GSH and anti-ferroptosis systems [28]
10.1007/s00134-022-06731-z 130 PatsakiI.AvgeriV.RigouliaT.ZekisT.KoumantakisG
However, it is also possible that any GABA+ effects in the larger SZ group are masked by heterogeneity within the broad diagnostic group, or altered by medication as suggested by the exploratory analysis
Large doses may cause diarrhoea and other gastro-intestinal disturbances
This cascade of events induces the nuclear translocation of FOXO1, thereby enhancing its transcriptional activity [84]
