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Many DEEP programs are in place to assist municipalities and residents navigate flooding, climate change, resilience, hazard mitigation, and risk management

The sleep deprivation pro-atherogenic effect in animal model of sleep fragmentation is mediated, at least in part, by reduced hypothalamic release of hypocretin (i.e., orexin), a wake-inducing neuropeptide, which limits the production of leukocytes (monocytes and neutrophils) and atherosclerosis development, and has been inversely associated with the risk of myocardial infarction, heart failure, and obesity 205

, & Chittasupho, C

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Acknowledgments The authors thank Akiko Yamashita, Chihiro Ishizaki, Yoriko Setsuda, and Maki Ozone at Kyoto University Hospital Department of Nephrology for their excellent technical assistance

From this class, prostaglandin-D 2 synthase and prostaglandin-E 2 synthase catalyze the cleavage of prostaglandin H 2, forming prostaglandin-D 2 or E 2 [216]