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doi: 10.3390/cells14211704, 27
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Sphingosine-1-phosphate differently regulates the cytokine production of IL-12, IL-23 and IL-27 in activated murine bone marrow derived dendritic cells

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It also plays a crucial role in the production of endothelium-derived relaxing factor (EDRF) , primarily nitric oxide
This is why a test, dont guess approach is the most cost-effective way forward