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The copperzinc superoxide dismutase activity in selected diseases

Here, we present compelling results demonstrating a functional connection between altered TrkB signalling in iSPNs and changes in glutathione metabolism, particularly the enzyme GSTO2, at the pre-symptomatic stage, causing an early increase in DA followed by progressive degeneration and the onset of hyperkinetic symptoms

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Kennecke H, Yerushalmi R, Woods R, Cheang MCU, Voduc D, Speers CH, et al

Therefore, intake of such natural antioxidants may give protective effect against free radical induced diseases