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Neurotrauma 174 PovlishockJ.BeckerD.ChengC.VaughanG

Research has demonstrated that the receptor for AGEs (RAGE) suppresses osteoblast proliferation by disrupting multiple signaling pathways, such as the PI3 kinase, extracellular signal-regulated kinase (ERK), and Wnt pathways (Zhou et al., 2023)

Unlike most proteins produced from nuclear DNA, MOTS-c is encoded directly inside the mitochondria the energy-producing structures inside cells

This activation and repression of glutathione metabolism play a crucial role in maintaining cellular redox homeostasis and detoxification by coordinating transcriptional responses to oxidative stress

Melatonin is an antioxidant, anti-inflammatory, free radical scavenger, circadian rhythm regulator, and sleep hormone

Lu H, Forbes RA, Verma A
