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The efficacy of PRP varies depending on the current condition of your follicles

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There was even a theory originally put out in the 1950s called The Free Radical Theory of Aging* which basically held that we age by rusting from within, due largely (but not exclusively) to free radical damage

10.1007/s11064-016-1848-6 98 PengW.ZhuZ.YangY.HouJ.LuJ.ChenC.et al (2021)

Since acitretin has a less terminal elimination half-life and fewer lipophilic properties, its effect may be limited leading to early recurrence

it is just calibrated to the male level of oxytocin and the male brains response to oxytocin