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Description
ZO-1, Zonula Occludens-1
11 , eadv4238 (2025)

10.1002/jcb.29179 94 QiuB.AckermanD.SanchezD

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Consequently, selenium intake varies between countries

By inhibiting this enzyme, A1AT decreases the production of superoxides, contributing to a reduction in the overall ROS burden in tissues and helping to limit oxidative damage ( Furthermore, A1AT binds to metal ions such as copper (Cu) and iron (Fe), which catalyze ROS production via the Haber-Weiss and Fenton reactions