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doi: 10.1111/j.1567-1364.2012.00826.x 82

Human metabolic individuality in biomedical and pharmaceutical research

A number of mercapturates derived from halogenated alkenes are converted to the corresponding sulfoxides by cytochrome P450 3A (but apparently not by FMOs) (Birner et al., 1998, Werner et al., 1995a, Werner et al., 1995b, Werner et al., 1996)

This imbalance compromises the integrity of the intestinal lining, leading to increased intestinal permeability, commonly known as "leaky gut" though the cited source actually discusses mRNA vaccines and their delivery strategies

Handling: Wear appropriate personal protective equipment (PPE) including gloves and safety eyewear

10.1186/s40168-020-00823-y 106 JingZ
