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Adequate B vitamin status supports serotonin and dopamine production, nervous system integrity, and stress resilience

The function of neuromelanin is currently unknown, but it is relevant that the substance accumulates in the SN of aging primates [4, 21]

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In conclusion, the decision to explore glutathione for skin lightening should be carefully considered under a qualified dermatologists guidance

14 Although opioids represent the primary pharmacologic therapy for moderate-to-severe pain, there are numerous other indications for opioid use, including sedation (Table S1 in the Supplementary Appendix, available with the full text of this article at NEJM.org)

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