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doi: 10.1016/j.intimp.2007.04.005 88 LeeWRKimKHAnHJKimJYHanSMLeeKGet al
10.1021/acs.jmedchem.3c00770 55 CiriminnaR.PagliaroM
10.3390/biomedicines9010067 184 RashidianA.DejbanP.Karami FardK.AbdollahiA.ChamanaraM.DehpourA.et al (2020)
Since the organ-type alone cannot explain the sensitivity towards the GNE/BMS combination, we correlated the responsiveness to genomic alterations using a subset of the most commonly occurring and intensively studied cancer genes (Supplementary Table 3)
The overactivation of glutamate receptors further amplifies excitotoxicity and calcium overload, ultimately leading to mitochondrial failure and cell death (Pawluk et al., 2020)
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Therefore, we tested whether this was true for the LEC2-induced open chromatin
