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Alterations in the concentrations of intracellular and extracellular ions are linked to the production of CSD

Treatments of CF disease Antibiotics resistance of pathogens infecting CF patients is a hallmark of the disease

The extracellular matrix (ECM) produced by CAFs interacts with cancer cells to influence tumor growth and invasion ( Therefore, targeting the crosstalk between tumors and relevant cells in the TME to improve the tumor immune microenvironment and enhance metabolic competition between tumors and the immune system will be a new focus for future research

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Kang D, Lim Y, Ahn D et al (2025) Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis

Moreover, minocycline has been reported to exert its anti-inflammatory actions by modulating microglial activation through SIRT1 activation (Soczynska et al