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Key findings from this phase 2 obesity trial included: Mean weight reduction of up to approximately 24.2% at the highest dose (12 mg) after 48 weeks Dose-dependent reductions in body weight across all active treatment arms Significant reductions in waist circumference, blood pressure, and lipid parameters Improvements in fasting glucose and insulin resistance markers A separate phase 2 trial in adults with type 2 diabetes (published in 2023) demonstrated meaningful HbA1c reductions alongside substantial weight loss, suggesting potential dual utility in both obesity and glycaemic management
Eli Lilly and Novo Nordisk have waged war on telehealth companies marketing compounded versions of their blockbuster diabetes and obesity medications
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The Food and Drug Administration approved the pill nearly two months ago
Interestingly, whole-body, or CNS-specific, GLP-1R knockout in a mouse did not result in sizable change in body weight, fat mass or hyperphagia
With each new production batch, the vial cap and crimp colours change, creating a visible batch identifier
