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Cost-effectiveness of semaglutide in patients with obesity and cardiovascular disease

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GLP-1s anti-apoptotic effects GLP-1 RAs exhibit strong anti-apoptotic effects by activating the PI3K/Akt pathway, which promotes cell survival by inhibiting pro-apoptotic factors such as Bax and caspase-3, while upregulating anti-apoptotic proteins like Bcl-2 (104106)

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doi: 10.1016/j.tem.2024.01.007

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It plays a crucial role in regulating blood sugar levels, appetite, and digestion

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At the end of treatment, mice were subject to tissue collection under anesthesia with intraperitoneal injection of pentobarbital (35 mg/kg)

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