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Disease-disease interactions: molecular links of neurodegenerative diseases with cancer, viral infections, and type 2 diabetes

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Diabetologia 58(3):429442

The authors suggest a compensatory relationship: given that GLP-1 has strong effects on appetite suppression, glycemic regulation, and body weight loss in females, it seems plausible that lower Glp1 densities in the GrO of females over males are compensated by sufficient and necessary estrogen actions on appetite regulation