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While Ozempic shares its active ingredient with some weight loss medications, it is not approved for this use

Constipation rates vary by formulation and dose, with approximately 5-15% of patients on Ozempic and 11-24% of patients on Wegovy reporting constipation

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Example 6 Arg34GLP-1 (9-37) carries out the modification of terminal amino group: 1g Boc-His (Trt) -Aib-OH was dissolved in 10mL of dichloromethane, and 0.37g DIC was added