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muciniphila facilitates L-aspartate transportation in the gut-liver axis for the activation of the liver kinase B1 (LKB1)-AMPK pathway and increases lipid oxidation, thereby ameliorating liver steatosis (Rao et al., 2021)

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In contrast, semaglutide acts as a glucagon-like peptide-1 receptor agonist (GLP-1 RA), modulating immune responses, reducing inflammation, and preserving gut barrier integrity