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Y., Peters, T

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A simple way to monitor hydration is the color of your urine after you wake up straw- or lemonade-colored urine is a sign of appropriate hydration, while dark-colored urine, about the color of apple juice, indicates dehydration

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Enteroendocrine cells (EECs), the microbiota, and metabolites produced by the microbiota constitute a complex signaling system [13] that involves the enteric plexus, CNS afferents and efferents, and the modulation of numerous brain nuclei like the nucleus tractus solitarius, hypothalamus, thalamus, and many others directly involved in the control of glucose and energy homeostasis [14]

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doi:10.1016/j.molmet.2015.07.008 The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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But once the shortage ends, the patent is back to being enforced, and no other copies are allowed

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