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23,24 A post hoc analysis of the Look AHEAD trial reported that at least 10% weight loss in the first year was associated with a 21% lower risk of major adverse cardiac events

The starting dose is 2.5 mg once weekly via subcutaneous injection for the first 4 weeks

To this end, patients were required to either have coverage (Optum) or have prior visits (MGB) at least two years prior to their initial PD diagnosis

Author response: We thank reviewer 1 for these comments and have further addressed this issue beneath reviewer 2s relevant comment

[14] Beyond mechanical factors, obesity contributes to joint disease through metabolic and inflammatory pathways
To Novo, that represented a shipment of the diabetes drugs destined for Egypt
